Menthol in Nicotine Salt E-JuicesMenthol in Nicotine Salt E-Juices

Menthol liquid is a great addition to any vape juice. It enhances the taste of certain fruit flavors while providing a refreshing experience. It is also an essential part of many nicotine salt e-juices.

It is known that menthol triggers cold receptors, causing a cooling sensation when it touches skin. This is why it is often used in external preparations for rubbing painful muscles. It is also a popular ingredient in mouth fluids because of its cool feeling and freshness. It is not recommended to vape menthol alone because of its harshness on the throat.

Cool and Refreshing: Menthol Liquid for a Crisp Hit

However, menthol can be used in combination with other ingredients to make it milder and less harsh on the throat. This can be done by using a lower wattage and coil resistance or by choosing a higher VG % in the e-juice mix.

In the current study, adult male C57BL/6J mice were randomly assigned to one of three exposure groups: propylene glycol and vegetable glycerol as vehicle control (Veh cont); PG/VG with 4% nicotine without menthol (Nico); and PG/VG with 4% nicotine and 10% menthol flavorings (Nico + ment). The results show that long-term vapor exposure to ENDS with a menthol flavor significantly enhanced sociability and preference for social novelty in comparison to PG/VG with nicotine alone. This effect was associated with the activation of AMPK in the hippocampus and of a number of cytokines in the serum.